Repeated Head Injuries Linked to Brain Damage, New Study Finds

Islamabad (Qudrat Daily) – Recent research reveals that high levels of inflammation caused by repeated head injuries are linked to damage in the brain’s white matter, particularly in the limbic system.

Published in the journal *Neurology*, the study explains why some former athletes develop cognitive and behavioral disorders later in life. Senior researchers noted that contact sports such as football, rugby, and martial arts, where the head is frequently impacted, have previously been associated with an increased risk of neurodegenerative diseases, including chronic traumatic encephalopathy (CTE).

For this study, scientists examined 223 men, 170 of whom had played football at collegiate or professional levels, all in their 50s. Blood and spinal fluid samples were collected, and MRI scans were performed to assess brain structure and examine signs of CTE.

Results showed that about 59% of the footballers experienced cognitive decline, and 58% had difficulties controlling behavior and emotions. In contrast, participants not involved in sports showed no cognitive decline, and only 2% reported issues with emotional regulation.

Researchers concluded that repeated head injuries lead to elevated inflammation, which damages the brain’s white matter, particularly the limbic system responsible for memory, emotion, and motivation. This damage was also associated with memory deficits, especially in the 57 footballers identified as having a high likelihood of developing CTE.

Senior investigators emphasized that targeting inflammation could potentially reduce the risk of these brain changes and mitigate the progressive symptoms associated with repeated head injuries.